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Melatonin has been shown to have anti-inflammatory effects, among a variety of actions. Melatonin lowers cells destruction during inflammatory responses by a number of ways. Thus melatonin, by virtue of its ability to straight scavenge toxic totally free radicals, reduces macromolecular damages in all body organs. The totally free radicals as well as reactive oxygen as well as nitrogen species known to be scavenged by melatonin include the highly harmful hydroxyl radical, peroxynitrite anion, and hypochlorous acid, to name a few. These representatives all add to the inflammatory feedback and associated cells destruction. Furthermore, melatonin has other means to decrease the damage arising from swelling.
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